Virtual Reality as Nonpharmacologic Pain Management Among Hospitalized Inpatients. A randomized controlled trial of Virtual Reality vs Standard of Care
This randomized control trial seeks to replicate and extend our previous studies by testing the efficacy of the EaseVRx in reducing pain in hospital inpatients across all services as compared to standard of care treatment.
Principal Investigator:
Mark Powers, PhD
Roles:
Megan Douglas, PhD, Co-Investigator
Ann Marie Warren, PhD, Co-Investigator
Funding: Applied VR
Closed-loop Neuromodulation to Treat PTSD
The purpose of this open-label pilot study is to provide an initial assessment of the safety of using a new device to deliver vagus nerve stimulation to reduce symptom severity in participants with PTSD. Additionally, the study will assess the prospective benefit of the system and garner an initial estimate of the effect size for a subsequent trial.
Principal Investigators:
Michael Foreman, MD
Michael Kilgard, PhD
Roles:
Megan Douglas, PhD, Study Therapist
Mark Powers, PhD, Co-Investigator
Ann Marie Warren, PhD, Co-Investigator
Funding: Defense Advanced Research Projects Agency (DARPA): Space and Naval
Warfare Systems Center, Pacific
Targeted Plasticity Therapy for Upper Limb Rehabilitation in Spinal Cord Injuries
The study will provide an initial evaluation of the use of the ReStore implanted stimulator in the context of spinal cord injuries. The study will help to assess the prospect that VNS coupled with rehabilitation in participants suffering from upper extremity paresis after a spinal cord injury is a potentially effective treatment to improve recovery of upper limb motor function.
Principal Investigators:
Rita Hamilton, MD
Michael Kilgard, PhD
Roles:
Mark Powers, PhD, Co-Investigator
Funding: National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR)
Wireless Nerve Stimulation Device to Enhance Recovery after Stroke
The study will provide an initial evaluation of the use of the ReStore implanted stimulator in the context of spinal cord injuries. The study will help to assess the prospect that VNS coupled with rehabilitation in participants suffering from upper extremity paresis after a spinal
Principal Investigators:
Rita Hamilton, MD
Michael Kilgard, PhD
Roles:
Mark Powers, PhD, Co-Investigator
Funding: National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR) NIDILRR
Prevention of Posttraumatic Stress: A RCT of Modified Brief Prolonged Exposure Therapy (Brief PE) During Inpatient Rehabilitation Post Spinal Cord Injury (SCI)
The overall goal of this project is to test a brief intervention (three 60-minute sessions) to reduce psychological distress after SCI and to mitigate long-term post-SCI distress including PTSD.
Principal Investigator:
Mark Powers, PhD
Roles:
Megan Douglas, PhD, Co-Investigator
Ann Marie Warren, PhD, Co-Investigator
Funding: National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR)
Prevention of Posttraumatic Stress: A Randomized Controlled Trial of Brief Prolonged Exposure Therapy for Injured Individuals Admitted to a Level I Trauma Center
Principal Investigator:
Ann Marie Warren, PhD
Roles:
Megan Douglas, PhD, Co-Investigator
Mark Powers, PhD, Co-Investigator
Claire Bird, PhD, Study Therapist
Funding: Department of Defense CDMRP Traumatic Brain Injury and Psychological Health Research Program (TBIPH) Clinical Trial Award
Targeted Plasticity Therapy for the Treatment of Post-traumatic Stress Disorder
Principal Investigators:
Mark Powers, PhD
Jasper Smits, PhD
Seth Hays, PhD
Roles:
Megan Douglas, Co-Investigator
Ann Marie Warren, Co-Investigator
Funding: Department of Defense CDMRP Traumatic Brain Injury and Psychological Health Research Program (TBIPH) Clinical Trial Award
Long-Term Outcomes of Extracorporeal Membrane Oxygenation Patients in an Integrated System in Texas (LTO-ECMO)
The primary objective is to collect longitudinal measures of psychological health, cognitive function, and health related quality of life in patients treated with ECMO following hospital discharge over a 36-month period. Support is for research staff to enroll participants and collect assessments.
Principal Investigator:
Megan Douglas, PhD
Roles:
Mark Powers, PhD, Co-Investigator
Ann Marie Warren, PhD, Co-Investigator
Funding: Cardiovascular Research Review Committee at Baylor Scott & White Research Institute
Professional Well-Being of Operating Room Personnel: A Qualitative Investigation to Reduce Medical Errors and Enhance Clinician Moral Resilience
The objective of this project is to examine perceived supports and benefits in the operating room that target the National Academy of Medicine’s model to increase professional well-being and resilience. This study aims to look at the following areas to inform an understanding of how addressing the well-being of healthcare workers may, in turn, reduce medical errors in the operating room: (1) individual mediating factors, (2) workplace factors, and (3) systems-level factors.
Principal Investigator:
Ann Marie Warren, PhD
Funding: BSW Wellbeing in Medicine
Group Lifestyle Balance™ for Individuals With Traumatic Brain Injury
The purpose of this RCT is to examine the efficacy of a Group Lifestyle Balance™ (GLB) program adapted for people with traumatic brain injury (TBI) on primary (weight) and secondary outcomes at 3, 6, 12, and 18 months from enrollment into the program.
Principal Investigator:
Simon Driver, PhD
Roles:
Megan Douglas, PhD, Co-Investigator
Funding: National Institute on Disability Independent Living and Rehabilitation Research (NIDILRR)
Physician Well-Being: Burnout & Professional Fulfillment
Principal Investigator:
Jamile Ashmore, PhD
Roles:
Megan Douglas, PhD, Co-Investigator
Funding: The Heart Hospital Plano, Baylor Scott & White Health
Foundational Ingredients of Robotic Gait Training for People with Spinal Cord Injury During Inpatient Therapy (FIRST)
The purpose of the study is to examine intensity as a critical component of robotic gait training during inpatient rehabilitation for people with spinal cord injury.
Principal Investigator:
Chad Swank, PT, PhD
Roles:
Megan Douglas, PhD, Co-Investigator
Funding: National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR),
Administration for Community Living
Baylor Scott & White Traumatic Brain Injury Model Systems Center
Traumatic Brain Injury Model Systems Centers provide comprehensive, multidisciplinary services to people with traumatic brain injury (TBI) as a prerequisite for conducting research that contributes to the development of and access to evidence-based TBI rehabilitation with the ultimate goal of improving the health and function, community living and participation, and employment outcomes of people with TBI. TBIMS Centers generate new knowledge through site-specific research projects, collaborative projects, and contributions of data to the TBIMS national longitudinal database.
Principal Investigator:
Simon Driver, PhD
Roles:
Megan Douglas, PhD, Co-Investigator
Funding: National Institute on Disability Independent Living and Rehabilitation Research (NIDILRR)
Baylor Scott & White Spinal Cord Injury Model System
The SCI Model System grants five-year funding to national leaders in medical research and patient care that provide the highest level of comprehensive specialty services. The primary project involves an intervention/prevention for PTSD symptoms after acute SCI.
Principal Investigator:
Ann Marie Warren, PhD
Roles:
Megan Douglas, PhD, Co-Investigator
Mark Powers, PhD, Co-Investigator
Funding: National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR)
Employing a Stepped-Wedge Design to Implement an Evidence-Based Psychotherapy for PTSD in Six Large, Diverse Health Care Systems
This study will investigate whether Written Exposure Therapy (WET) can be disseminated and implemented in six health care systems across the United States. Approximately 485 providers across six health care systems will be trained in how to deliver Written Exposure Therapy (WET) through attendance at a virtual training hosted by the treatment developers. The study will provide consultation to providers following training to ensure competence via 12-weeks of 1-hour telephone consultation with WET experts and will measure provider fidelity and adaptation to WET. The team will assist sites in identifying obstacles to WET implementation through a facilitated learning collaborative and will track patient outcomes.
Principal Investigators:
Vanessa Simiola, PhD
Joan Cook, PhD
Roles:
Ann Marie Warren, PhD, Site PI
Funding:Patient Centered Outcomes Research Institute (PCORI)
Train and Empower a Community Health workforce to achieve equity and reduce disparities in mental health
The objective of this project is to evaluate the implementation of a scalable task-sharing model aimed at building capacity and supporting a racially diverse workforce of non-specialist providers to deliver evidence-based mental health interventions, ultimately contributing to the reduction of mental health disparities in their communities.
Principal Investigator:
Kathryn Sanchez, PhD
Roles:
Ann Marie Warren PhD, Site PI
Funding: National Institute of Mental Health (NIMH)
A National Look at the Psychological Impact of COVID-19
This project aims to identify the psychological responses of individuals who are impacted by
COVID-19 to examine the psychological impact of COVID-19 on the general population.
Principal Investigator:
Ann Marie Warren, PhD
Roles:
Megan Douglas, PhD, Co-Investigator
Mark Powers, PhD, Co-Investigator
Funding: Baylor Scott & White Dallas Foundation; W.W. Caruth, Jr. Fund at Communities Foundation of Texas
Acknowledgement: These projects are made possible by the collaborations the Trauma Research Center has with many BSWRI Investigators and research team members, as well as clinical staff and collaborators both internal and external to BSWH. We are grateful for all individuals who help make this research possible!
